Description
ISDIN Isdinceutics Retinal Intense is a powerful biphasic night serum designed to visibly renew and rejuvenate the skin while you sleep. Developed by ISDIN, this advanced anti-aging treatment combines retinaldehyde, melatonin, niacinamide, and bakuchiol to deliver high-performance skin renewal with optimal tolerance, even for sensitive skin.
Formulated with retinaldehyde, one of the most effective retinoids in skincare, this serum helps accelerate cell turnover and visibly reduce fine lines and wrinkles. Retinaldehyde is known to be more potent than retinol and works faster in the skin, delivering noticeable results in skin texture, tone, and firmness.
The innovative biphasic formula is activated upon use, preserving ingredient freshness and ensuring maximum effectiveness. When mixed, it creates a silky, smooth texture that absorbs easily into the skin, leaving a comfortable finish.
Melatonin works overnight to support the skin’s antioxidant defenses, helping repair daily damage caused by pollution, UV exposure, and environmental stressors. Niacinamide helps minimize dryness and irritation often associated with retinoids, improving skin comfort and hydration. Meanwhile, bakuchiol supports elasticity and firmness, enhancing the overall anti-aging effect.
With continued use, skin appears smoother, firmer, and more radiant, with visibly reduced wrinkles and improved texture. Clinical results show up to 43% reduction in wrinkles in 4 weeks, making it a highly effective solution for visible skin rejuvenation.
Key Benefits
- Reduces fine lines and wrinkles by up to 43% in 4 weeks
- Retinaldehyde boosts skin renewal and anti-aging performance
- Melatonin helps repair oxidative skin damage overnight
- Niacinamide improves hydration and reduces irritation
- Bakuchiol enhances firmness and elasticity
- Biphasic formula ensures freshness and optimal efficacy
- Smooth, silky finish suitable for all skin types
How to Use
Use in the evening routine. Dispense two pumps, mix both phases until uniform, and apply a thin layer to clean, dry skin. Avoid the eye contour, nose, and lips.

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